Anti-VEGF therapy is a modern treatment for retinal diseases such as:
The treatment is based on medications that block the action of a protein called vascular endothelial growth factor (VEGF). This protein stimulates the growth of new, fragile blood vessels that can leak fluid or blood into the eye tissues. This leads to swelling, damage to the central retina, and deterioration of vision.
At “Prostir Zoru” clinic, we perform treatment using two medications:
The intravitreal injection (IVI) regimen of Eylea or Vabysmo is selected individually by the doctor for each patient. In the initial stage of treatment, injections are usually given monthly. The number of injections needed to achieve improvement is also determined by your ophthalmologist.
Aflibercept is a protein antagonist of vascular endothelial growth factor (VEGF). It blocks growth factors, which helps reduce the growth of abnormal blood vessels, decrease swelling, and preserve visual function.
Faricimab also has this effect; however, in addition to it, it also reduces inflammatory processes and strengthens blood vessel walls. It blocks not only vascular endothelial growth factor A (VEGF-A), but also angiopoietin-2 (Ang-2) — a protein that contributes to vessel instability, inflammation, and increased permeability. Thanks to this dual action, the drug helps effectively control retinal swelling and the growth of pathological blood vessels.
The choice between medications is made individually and depends on the diagnosis, disease activity, response to previous treatment, and the specific characteristics of each patient.
Are there any contraindications?
How does it work?
Intravitreal injections are performed in an operating room under sterile conditions and local anesthesia. The procedure takes only a few minutes, after which you are examined again by the doctor and given further recommendations.
Are there any side effects?
Most patients tolerate intravitreal injections well. After the procedure, temporary side effects may occur, which usually resolve on their own within a few days:
Serious complications after anti-VEGF therapy are rare. If after the injection you experience severe eye pain, sudden deterioration of vision, marked redness, or increased light sensitivity, you should seek medical attention immediately.
Preserving vision is a combination of timely diagnosis, regular monitoring, and properly selected treatment. Modern medications expand the possibilities of helping patients; however, the most important factor remains an individual approach in each specific case.
Kushnir Nataliya
Ophthalmologist, Candidate of Medical Sciences